1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B0357R
    Diclazuril (Standard)
    Inhibitor
    Diclazuril (Standard) is the analytical standard of Diclazuril. This product is intended for research and analytical applications. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al.
    Diclazuril (Standard)
  • HY-W663230
    Eugenitin
    Inhibitor
    Eugenitin is a polyketide isolated from the fungus Mycoleptodiscus indicus that is related to the South American medicinal plant. Eugenitin inhibits Leishmania major with LD50=39.9 μM. Eugenitin has low cytotoxicity (IC50 >131 μM) against several human cancer cell lines.
    Eugenitin
  • HY-106585
    Cyclobendazole
    Cyclobendazole is a benzimidazole derivative against protozoan parasites. Cyclobendazole shows in vitro activities against Trichomonas vaginalis (30236) and Giardia lamblia (wt), with IC50 values of 1.1 and 0.047 μg/mL, respectively.
    Cyclobendazole
  • HY-155207
    Antileishmanial agent-23
    Inhibitor
    Antileishmanial agent-23 (compound G1/9) is a potent and selective trypanothione reductase (TR) inhibitor, with an IC50 of 2.24 ± 0.52 μM. Antileishmanial agent-23 inhibits the growth of Leishmania, Trypanosoma cruzi, and Trypanosoma brucei.
    Antileishmanial agent-23
  • HY-153732
    Insecticidal agent 2
    Inhibitor
    Insecticidal agent 2 (example 2) is a pesticide that exhibits potent growth-retarding activity against pests.
    Insecticidal agent 2
  • HY-N0059S6
    D-Arabinose-d6
    Inhibitor
    D-Arabinose-d6 is the deuterium labeled D-Arabinose (HY-N0059). D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
    D-Arabinose-d<sub>6</sub>
  • HY-121817R
    Sulfiram (Standard)
    Sulfiram (Standard) is the analytical standard of Sulfiram (HY-121817). This product is intended for research and analytical applications. Sulfiram, an ectoparasiticide, is a weak aldehyde dehydrogenase (ALDH) inhibitor. Sulfiram can be used for the study of scabies.
    Sulfiram (Standard)
  • HY-108387
    Morantel citrate
    Inhibitor
    Morantel citrate is a veterinary anthelmintic agent that inhibits parasitic infections in cattle, sheep and goats. Morantel citrate paralyzes the nervous system of the parasite, helping the animal expel the dead parasite from the body.
    Morantel citrate
  • HY-117419
    (-)-Lavandulyl acetate
    Inhibitor
    (-)-Lavandulyl acetate is a nature product that can be found in Lavandula angustifolia. (-)-Lavandulyl acetate shows toxicity for mosquito vectors. (-)-Lavandulyl acetate can be used as mosquito larvicide.
    (-)-Lavandulyl acetate
  • HY-147535
    Antileishmanial agent-7
    Inhibitor
    Antileishmanial agent-7 (compound 23) is a potent antileishmanial agent. Antileishmanial agent-7 shows antileishmanial activity against Leishmania donovani and L-6, with IC50 values of 6.89 and 259 μM, respectively.
    Antileishmanial agent-7
  • HY-143322
    CRK12-IN-2
    Inhibitor
    CRK12-IN-2 (compound 2) is an inhibitor of CRK12. CRK12-IN-2 shows potency against Trypanosoma congolense and Trypanosoma vivax with EC50 values of 3.2 and 0.08 nM. CRK12-IN-2 can be used for the research of animal trypanosomiasis.
    CRK12-IN-2
  • HY-123686
    Ivermectin B1a monosaccharide
    Inhibitor
    Ivermectin B1a monosaccharide is a modified Ivermectin B1a (HY-126937). Ivermectin B1a monosaccharide is an antiparasite agent with a minimum concentration for full activity in Haemonchus contortus larval development of 0.001 μg/mL.
    Ivermectin B1a monosaccharide
  • HY-119893
    Diamfenetide
    Inhibitor
    Diamfenetide is used for the study of Fasciola hepatica infections in vitro. Diamfenetide leads to irreversible paralysis in vitro of immature and adult Fasciola hepatica.
    Diamfenetide
  • HY-N8338
    Pancixanthone A
    Inhibitor
    Pancixanthone A is a xanthone that can be isolated from Garcinia vieillardii. Pancixanthone A has antimalarial activity against chloroquino-resistant strains of Plasmodium falciparum with an IC50 of 1.6 μg/mL.
    Pancixanthone A
  • HY-132908
    Anti-ToCV agent 1
    Inhibitor
    Anti-ToCV agent 1 can be used as a potential anti-ToCV agent.
    Anti-ToCV agent 1
  • HY-N2970
    Burchellin
    Inhibitor
    Burchellin is a neolignan that can inhibit Trypanosoma cruzi.
    Burchellin
  • HY-N0769R
    Isopimpinellin (Standard)
    Inhibitor
    Isopimpinellin (Standard) is the analytical standard of Isopimpinellin. This product is intended for research and analytical applications. Isopimpinellin, an orally active compound isolated from Glomerella cingulata. Isopimpinellin blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene. Isopimpinellin possesses anti-leishmania effect.
    Isopimpinellin (Standard)
  • HY-147534
    Antileishmanial agent-6
    Inhibitor
    Antileishmanial agent-6 (compound 8m) is a potent antileishmanial agent. Antileishmanial agent-6 shows antileishmanial and cytotoxic activity against Leishmania donovani and L-6, with IC50 values of 0.54 and 10.2 μM, respectively.
    Antileishmanial agent-6
  • HY-123897
    Chamaejasmenin C
    Inhibitor
    Chamaejasmenin C, a biflavanone, shows nematicidal activity against second-stage juveniles (J2s) of B. xylophilus and B. mucronatus.
    Chamaejasmenin C
  • HY-155520
    Antileishmanial agent-19
    Inhibitor
    Antileishmanial agent-19 (Compound F27) is an antileishmanial agent, with a IC50 of 3.39 μM for L. donovani promastigotes. Antileishmanial agent-19 inhibits Leishmania prolyl-tRNA synthetase. Antileishmanial agent-19 inhibits host PI3K/Akt/CREB axis-mediated IL-10 secretion. Antileishmanial agent-19 induces autophagy-mediated apoptosis in L. donovani promastigotes. Antileishmanial agent-19 reduces parasite burden in L.d-infected animals.
    Antileishmanial agent-19

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